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为探讨儿童行为问题发生状况与外周血5-羟色胺(5-HT)浓度变化的关系,用Achenbach儿童行为量表筛查4～16岁儿童行为问题发生率,检测其外周血5-HT浓度,与正常儿童比较。结果,行为问题组5-HT浓度与正常组儿童无显著性差异(t=1.0860,P>0.05),内向性行为问题组儿童5-HT浓度显著高于正常组(t=2.4450,P<0.05),外向性行为问题组5-HT浓度低于正常组,但无显著性差异(t=0.2732,P>0.05),内向性行为问题组5-HT显著高于外向性行为问题组(t=2.1126,P<0.05)。提示,儿童行为问题的发生与外周血5-HT浓度改变有关,5-HT是儿童行为问题发生的物质基础之一。
To investigate the relationship between the occurrence of childhood behavioral problems and the changes of 5-HT concentration in peripheral blood, the Achenbach children’s behavior scale was used to screen the incidence of behavioral problems in children aged 4-16 years, and the levels of 5-HT in peripheral blood were detected. Compared with normal children. Results There was no significant difference in the concentration of 5-HT among children with behavioral problems (t = 1.0860, P> 0.05). The concentration of 5-HT in children with behavioral problems was significantly higher than that of normal children (t = 2.4450, P <0.05) (T = 0.2732, P> 0.05). The 5-HT level in the introverted behavioral problem group was significantly higher than that in the extroverted behavioral problem group (t = 0.2732, P> 0.05) 2.1126, P <0.05). Prompted that the occurrence of childhood behavioral problems and peripheral blood 5-HT concentration changes, 5-HT is one of the material basis for children’s behavioral problems.