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目的 探讨不稳定型心绞痛 (UA)的临床表现与冠状动脉病变形态学特性及近期预后的关系。方法 根据Braunwald分级积分标准确定UA患者的临床分级及积分 ,并将 96例UA患者分为A(积分 >3 ,n =81 )、B(积分≤ 3 ,n =1 5)两组 ,对照分析两组患者冠状动脉造影结果、住院 4周内心脏事件发生率及病死率。结果 ①冠状动脉造影结果分析显示 :冠状动脉复杂性病变 (偏心性狭窄或伴有溃疡、弥漫性不规则血栓形成及完全闭塞 )积分A组高于B组 (2 .458± 1 .1 4对 1 .444± 0 .88,P <0 .0 5) ,相差有显著性 ;②住院 4周内心脏事件总发生率A组高于B组 (2 3 .5 %对 6 .7% ,P >0 .0 5)。结论 提示UA临床分级积分可作为评估UA患者缺血相关血管病变复杂性及近期预后的重要预测因子
Objective To investigate the relationship between the clinical manifestations of unstable angina pectoris (UA) and the morphological features of coronary artery lesions and its prognosis. Methods The clinical grade and integral of UA patients were determined according to the criteria of Braunwald grading and the 96 UA patients were divided into two groups: A (score> 3, n = 81), B (score ≤ 3, n = 15) The results of coronary angiography in two groups of patients, the incidence of cardiac events within 4 weeks of hospitalization and case fatality rate. Results ①Coronary angiography showed that the integral of coronary complex lesions (eccentric stenosis or ulcer, diffuse irregular thrombosis and complete occlusion) was higher in group A than in group B (2.458 ± 1.14 pairs 1.444 ± 0.88, P <0.05), the difference was significant; ②The incidence of cardiac events within 4 weeks of hospitalization was higher in group A than in group B (23.5% vs. 6.7%, P > 0 .0 5). The results suggest that clinical UA score can be used as an important predictor of the complexity and recent prognosis of ischemic-related vascular lesions in patients with UA