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目的探讨儿童传染性单核细胞增多症(IM)的临床特点。方法回顾性分析2005年8月-2009年8月收治的151例IM患儿的症状、体征、实验室检查及治疗效果。结果 IM临床表现以发热、咽峡炎、肝脾和淋巴结肿大最常见,鼻塞、眼睑浮肿也是重要体征。外周血出现异型淋巴细胞及EBV-IgM抗体检测可帮助确诊。更昔洛韦治疗IM效果确切。结论应重视IM临床特点,有助于早期诊断并提高确诊率,应用更昔洛韦治疗值得推广。
Objective To investigate the clinical features of childhood infectious mononucleosis (IM). Methods Retrospective analysis of symptoms, signs, laboratory tests and therapeutic effects of 151 cases of IM patients admitted from August 2005 to August 2009 were retrospectively analyzed. IM clinical manifestations of fever, angina, liver and spleen and enlarged lymph nodes most common, nasal congestion, eyelid edema is also an important sign. Peripheral blood showed abnormal lymphocytes and EBV-IgM antibody test can help confirm the diagnosis. Ganciclovir treatment of IM effect is exact. Conclusions Should pay attention to the clinical features of IM, help to early diagnosis and improve the diagnosis rate, the application of ganciclovir therapy worth promoting.