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目的综合评估中青年突发性聋(SSHL)患者与全身低血压的关系。方法选择28例确诊为SSHL未经治疗的中青年(50岁以下)患者为实验组,均行听力学、即时血压、心率、24h动态血压连续监测、脂质代谢参数等检查。同时选择30例年龄、性别相匹配的正常血压非SSHL者为对照组进行同等处理。结果实验组平均的即时和动态血压(SBP、DBP)都显著低于对照组。两组在心血管疾病高危因子的统计差异不显著。实验组的低血压患病率显著高于对照组。结论全身性低血压的存在可引起耳蜗微循环的低灌注,而耳蜗缺血很可能是中青年SSHL患者的发病机制之一,尤其是耳蜗末梢顶转的血供会直接影响到低频听力。对此类患者的血压动态监测和限制使用血管扩张药是很有必要的。
Objective To evaluate the relationship between generalized hypotension (SBL) and middle-aged and young people with sudden hearing loss (SSHL). Methods A total of 28 middle-aged and younger patients under 50 years of age who had not been treated with SSHL were selected as the experimental group. All patients were examined with audiometry, real-time blood pressure, heart rate, 24h ambulatory blood pressure monitoring and lipid metabolism parameters. At the same time select 30 age, gender-matched normotensive non-sshL for the control group for the same treatment. Results The average real-time and ambulatory blood pressure (SBP, DBP) of the experimental group were significantly lower than that of the control group. There was no significant difference between the two groups in the risk factors of cardiovascular diseases. The prevalence of hypotension in the experimental group was significantly higher than that in the control group. Conclusions The presence of systemic hypotension can cause hypoperfusion in the microcirculation of the cochlea. Cochlear ischemia may be one of the pathogenesis of middle-aged and young patients with SSHL. In particular, the blood supply of apical turn of the cochlear can directly affect low-frequency hearing. It is necessary to monitor the blood pressure and limit the use of vasodilators in these patients.