长期接触苯可出现以损害骨髓造血机能为主的毒作用,但对其作用机理至今尚未完全阐明。体内环核苷酸代谢物环磷酸腺苷(CAMP)除作为激素作用的第二信使发挥生物效应外,还有调节遗传基因的活动,促进mRNA的转录,影响酶的合成,从而起代谢调节作用。细胞内或血浆中CA- Long-term exposure to benzene can occur to damage the bone marrow hematopoietic toxic effects, but its mechanism of action has not been fully elucidated. In addition to acting as a second messenger of hormonal effects, cyclic adenosine monophosphate (CAMP) plays an important biological role in regulating the activity of genes, promoting the transcription of mRNA, and affecting the synthesis of enzymes, thus acting as a metabolic regulator . Intracellular or plasma CA-