人体鱼序列综合征(sirenomelia sequence)是一种严重的极罕见的下肢及多脏器先天畸形,除极个别存活案例外,大部分均于围产期死亡或者出生后很快死亡。本文报道尸检该综合征1例,结合文献对其病理特征、发病机制以及治疗、预后进行讨论。1材料与方法1.1临床资料孕妇32岁,因妊娠15+4周,孕检B超发现胎儿发育异常入院。孕妇孕2产0,有多次 The sirenomelia sequence is a very rare congenital deformity of the lower extremity and multiple organs, with the exception of very few cases of survival, most of which died during the perinatal period or soon after birth. This article reports autopsy of the syndrome in 1 case, combined with the literature on its pathological features, pathogenesis and treatment, prognosis are discussed. 1 Materials and Methods 1.1 Clinical data Pregnant women 32 years old, 15 + 4 weeks of pregnancy, pregnancy test found abnormal fetal B-hospital admission. Pregnant women 2 pregnant 0, there are many times