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在中国卵巢癌是女性恶性肿瘤中致死最多的肿瘤之一。卵巢癌是妇科第 3位常见癌 ,仅次于宫颈癌和子宫内膜癌 ,也是妇科恶性肿瘤首位死亡原因。由于缺少有效的筛选方案 ,且早期患者无症状 ,故 70 %以上病例就诊时已为晚期。虽然手术技术和传统化疗均有改进 ,但卵巢癌预后无显著改善 ,晚期患者长期生存率不超过 2 0 %。卵巢癌的病因学仍了解甚少 ,中国对其研究主要集中于卵巢癌的发病机制、救治生命有效的诊断和治疗措施 ,并对较多病例进行研究。此文总结中国对卵巢癌的基础研究以及其目前诊断和处理概况。
Ovarian cancer is one of the most lethal cancers in women in China. Ovarian cancer is the third common gynecological cancer, second only to cervical cancer and endometrial cancer, but also the leading cause of death in gynecological malignancies. Due to the lack of an effective screening program and no symptoms in the early stage, over 70% of cases are late. Although surgical techniques and traditional chemotherapy have improved, but no significant improvement in the prognosis of ovarian cancer, advanced patients with long-term survival rate of no more than 20%. Etiology of ovarian cancer is still poorly understood, and its research in China mainly focuses on the pathogenesis of ovarian cancer, effective diagnosis and treatment of life-saving treatment, and more cases are studied. This article summarizes the basic research on ovarian cancer in China and its current diagnosis and treatment profile.