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我院1973~1992年共为725例慢性肾功能衰竭患者施行900例次同种异体尸体肾移植术。其中多次移植117例150次。年龄最大67岁,最小16岁。术后免疫抑制剂的使用,1984年以前为硫唑嘌呤和强的松二联用药;1985年起为环孢素A、硫唑嘌呤和类固醇三联用药。前者1年人肾存活率(人、肾均存活)68.55%,后者为89.68%。全组死亡共计202例。术后外科并发症有尿漏、肾破裂、动脉狭窄、血管栓塞、肾动脉破裂、膀胱出血、皮下出血及肾积水;内科并发症主要为感染。认为环孢素A的使用,使人、肾存活率大大提高。本文还就一些存有争议的问题进行了讨论。
Our hospital from 1973 to 1992 a total of 725 patients with chronic renal failure in 900 cases of allogeneic cadaveric kidney transplantation. Among them, 117 cases were transplanted 150 times. The oldest is 67 years old, the youngest is 16 years old. The use of postoperative immunosuppressive agents, before 1984 for azathioprine and prednisone dual drug; since 1985 for the cyclosporin A, azathioprine and steroid triple therapy. The former one-year survival rate of human kidney (human, kidney are alive) 68.55%, the latter was 89.68%. A total of 202 deaths in the whole group. Postoperative surgical complications of urinary leakage, renal rupture, artery stenosis, vascular embolism, renal artery rupture, bladder hemorrhage, subcutaneous hemorrhage and hydronephrosis; medical complications mainly infection. Cyclosporine A that the use of people and kidney survival rate greatly increased. This article also discusses some controversial issues.