病例摘要患者,男性,53岁。于1988年5月12日入院。18年前开始劳累后双侧跖趾关节红肿、疼痛。首次发病为右侧第一跖趾关节,以后又累及对侧。多自夜间开始发作,自服“安乃近”、“阿斯匹林”后4～6周症状逐渐缓解。开始每年发作1～2次,以后偶累及膝、踝关节。近来发作渐频繁,且逐渐变为持续性。10年前开始服用地塞米松4.5mg/日,隔2周用4～6周, Case Summary Male, 53 years old. Admitted to hospital on May 12, 1988. Bilateral metatarsophalangeal joints became inflamed and sore after 18 years ago. The first incidence of right first metatarsophalangeal joint, and later involved the contralateral. More from the night began to attack, self-service “metamizole”, “aspirin” after 4 to 6 weeks symptoms gradually eased. Start an episode of 1 or 2 times a year, after occasional knees, ankles. The recent onset of more frequent, and gradually become persistent. 10 years ago started taking dexamethasone 4.5mg / day, every 2 weeks with 4 to 6 weeks,