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目的:探讨高脂血症在急性胰腺炎发病中的临床意义。方法:根据病因筛选高脂血症相关性胰腺炎患者28例作为Ⅰ组,胆源性急性胰腺炎患者84例作为Ⅱ组,比较2组入院时及治疗7d血清三酰甘油、高密度脂蛋白、低密度脂蛋白、载脂蛋白A-Ⅰ以及血尿淀粉酶的差异。结果:Ⅰ组血清三酰甘油明显升高,治疗前、后与Ⅱ组比较,差异均有统计学意义(P<0.05)。结论:高脂血症相关性胰腺炎较胆源性胰腺炎更易反复发作,反复发作时血尿淀粉酶增高不明显,高脂血症相关性胰腺炎的治疗需注意改善血液循环紊乱及细胞膜功能的药物应用。
Objective: To investigate the clinical significance of hyperlipidemia in the pathogenesis of acute pancreatitis. Methods: According to the etiology, 28 patients with hyperlipidemia-related pancreatitis were selected as group Ⅰ and 84 patients with biliary acute pancreatitis as group Ⅱ. Serum triglyceride, high density lipoprotein , Low density lipoprotein, apolipoprotein A-Ⅰ and hematuria amylase. Results: Serum triglyceride was significantly increased in group Ⅰ. There was significant difference between group Ⅱ and group Ⅱ before and after treatment (P <0.05). Conclusions: Hyperlipidemia-related pancreatitis is more likely to recurrent than biliary pancreatitis, and the increase of hematuria amylase is not obvious when recurrent. The treatment of hyperlipidemia-related pancreatitis should pay attention to the improvement of blood circulation disorder and cell membrane function Drug application.