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目的分析>70岁的老年肺癌患者临床特征及其预后相关因素。方法收集2003年1月至2012年1月期间住院的110例肺癌患者的资料,分成>70岁(老年组,50例)与≤70岁(非老年组,60例)两组,比较两组的生存率及影响预后的因素。结果老年组和非老年组的1、2、3、4年生存率分别为74.0%、53.8%、11.6%、5.8%和81.4%、61%、41.9%、22.8%,差异无统计学意义(P>0.05)。单因素分析显示,分期、KPS评分、有无体重减轻是影响老年组肺癌患者预后的因素。多因素分析显示,分期、有无体重减轻是影响老年组预后的相关因素。结论分期、有无体重减轻是影响老年肺癌的独立预后因素,正确的分期结合功能状态评分,对老年肺癌的治疗具有指导意义。
Objective To analyze the clinical characteristics and prognostic factors of elderly patients with lung cancer over the age of 70 years. Methods The data of 110 hospitalized patients with lung cancer from January 2003 to January 2012 were collected and divided into two groups: those aged> 70 years (aged group, 50 cases) and ≤70 years (non-aged group, 60 cases) Survival rate and prognostic factors. Results The 1, 2, 3, 4-year survival rates of the elderly and non-elderly groups were 74.0%, 53.8%, 11.6%, 5.8% and 81.4%, 61%, 41.9% and 22.8% respectively, with no significant difference P> 0.05). Univariate analysis showed that staging, KPS score, with or without weight loss were the factors affecting the prognosis of elderly patients with lung cancer. Multivariate analysis showed that staging, with or without weight loss is related to the prognosis of the elderly related factors. Conclusions Staging and weight loss are independent prognostic factors for elderly patients with lung cancer. Correct staging combined with functional status score is instructive for the treatment of elderly patients with lung cancer.