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目的观察正常妊娠妇女和妊娠期血小板减少症(GT)妇女血小板(PLT)计数及其平均血小板体积(MPV)的变化。方法采用日本Sysmex XT-2000 i血细胞分析仪分别对正常孕妇(40例)、GT妇女及其新生儿(32例)、对照组(正常非孕妇女40例)的血液标本进行PLT计数及MPV测定,并进行统计学分析。结果妊娠期GT妇女随着孕周的增加PLT计数呈进行性下降,并低于正常孕妇组,并明显低于对照组;MPV偏高于正常孕妇组,并明显高于正常对照组。结论 GT组孕妇在整个孕期过程中虽然属于自限性的变化,但PLT减少仍然存在出血的可能性。因此,随时观察GT组PLT及MPV的变化,对孕妇及其胎儿的安全有重要的意义。
Objective To observe the changes of platelet count (PLT) and mean platelet volume (MPV) in women with normal pregnancy and gestation thrombocytopenia (GT). Methods The blood samples of normal pregnant women (40 cases), GT women and their newborns (32 cases) and control group (40 cases of normal non-pregnant women) were measured by PLT and MPV in Japan by Sysmex XT-2000 i hematology analyzer. , And statistical analysis. Results The gestational PLT count of GT women decreased progressively with gestational weeks and was lower than that of normal pregnant women and significantly lower than that of control group. MPV was higher than that of normal pregnant women and significantly higher than that of normal pregnant women. Conclusion Although pregnant women in GT group are self-limiting during pregnancy, there is still a possibility of PLT reduction. Therefore, it is of great significance to observe the changes of PLT and MPV in GT group to the safety of pregnant women and their fetus.