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炎症性肠病(IBD)是一种病因不明,反复发作性的肠道特异性疾病。随着遗传因素、环境因素与免疫反应异常等发病机制方面研究的不断进展,IBD的治疗发生了重大的变化,其中直接改善肠道微环境逐渐受到重视。在动物模型和人体寄生虫感染研究中,有丰富的资料支持寄生虫感染有免疫调节作用,近来这个概念已经用来治疗IBD,不断有肠道蠕虫治疗IBD的报道。现就肠道蠕虫治疗IBD的研究作一综述。
Inflammatory bowel disease (IBD) is an ill-defined, recurrent intestinal-specific disorder. With the continuous progress of the research on the pathogenesis of genetic factors, environmental factors and immune response abnormalities, the treatment of IBD has undergone significant changes, and the direct improvement of gut microenvironment has been paid more and more attention. In animal models and human parasitic infections, there is a wealth of information to support the immunomodulatory effect of parasitic infections. Recently, this concept has been used to treat IBD and there are reports of IBD continuing to be treated by intestinal worms. Now on the intestinal worm treatment of IBD to make a review.