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妊娠高血压(PIH)的病因虽仍不清楚,但其症状与母胎盘血管阻力增强有关,血压(BP)增高认为是一种维持胎盘灌注的代偿。所以抗高血压治疗可导致子宫血管扩张,以避免胎盘循环的改变。二氢吡啶族的钙通道阻断剂特点是能影响Ca~(++)向细胞内流入,因此这类药物包括Nifedipins(硝炎吡啶)和Nitrendipine (NTD),在临床显示出其对周围血管扩张的效果,并对原发性高血压似乎有效。最近的体外试验证实了NTD有效地使人类子宫松弛同样使胎儿胎盘血管扩张。为此,作者对NTD作了预测试验。本试验包括10名孕32～42周的患者,既往BP正常。孕28周后BP>150/90mmHg,在卧床休息1(?)
Although the cause of pregnancy-induced hypertension (PIH) remains unclear, the symptoms are associated with increased resistance to maternal and placental vascular disease. Increased blood pressure (BP) is considered as a compensatory measure to maintain placental perfusion. So antihypertensive treatment can cause uterine blood vessels to dilate, in order to avoid changes in the placental circulation. Dihydropyridine calcium channel blockers are characterized by their ability to affect Ca ~ (++) influx into cells. Therefore, such drugs include Nifedipins and Nitrendipine (NTD), which have been shown clinically to peripheral blood vessels Expansion of the effect, and seems to be effective in patients with essential hypertension. Recent in vitro tests confirm that NTD effectively relaxes the human uterus and also dilates fetal placental blood vessels. To this end, the author made a prediction test NTD. The trial included 10 patients 32 to 42 weeks pregnant, previous BP normal. 28 weeks after pregnancy BP> 150 / 90mmHg, resting in bed 1 (?)