AIM:To evaluate the role and limitation of fast multiplanarspoiled gradient-recalled(FMPSPGR)MR dynamiccontrast scanning in the follow-up of patients with HCCtreated by transarterial chemoembolization CTACE).METHODS:Twenty-two patients with 24 HCC lesionsconfirmed by biopsy or surgical resection underwentMR imaging in 4-9wks after TACE with a superconducting1.5 T MR scanner,including SE T_1WI,T_2WI and FMPSPGRdynamic contrast scanning.The signal intensities of alllesions on SE T_1WI,T_2WI and the enhancement patternson FMPSPGR dynamic contrast scanning were observed,and the comparison was made between MRI findingsand pathological results in all the cases.RESULTS:Of the 24 lesions,the signal intensities werevarious on SE T_1WI and T_2WI.On T_1WT,13 lesionsappeared as hyperintense,4 lesions were isointenseand the other 7 lesions were hypointensese.Histologically,hyperintense lesions showed on T_1WIwere viable tumor or hemorrhage;isointensities werecoagulative necrosis or inflammatory infiltration;hypointensities were tumor,liquified necrosis,coagulative necrosis or inflammatory infiltration.OnT_2WI,15 lesions appeared as hyperintense,3 lesionswere isointense and the other 6 lesions werehypointensese.Hyperintense lesions showed on T_2WIwere residuals of viable tumor,hemorrhage,liquefiednecrosis or inflammatory infiltration;isointense lesionswere residuals of viable tumor or inflammatoryinfiltration;hypointense lesions were coagulativenecrosis.On FMPSPGR dynamic contrast scanning,18of the 24 lesions enhanced on early-phase dynamicscanning corresponding to residuals of viable tumor andthe other 6 lesions had no enhancement at this phasebecause complete necrosis were seen in the histologicexamination.On delayed-phase dynamic scanning,6lesions had permanent enhancement appeared asinhomogeneous hyperintensity and both residuals ofviable tumor and inflammatory infiltration were foundby histologic examination.18 lesions were hypointense at this phase and 8 of them coexisted with peripheralring-like enhancement of the lesions resulting fromviable tumors or inflammatory infiltration.CONCLUSION:FMPSPGR MR dynamic contrast scanningcan reflect the pathologic changes of HCC treated byTACE.Especially,early-phase dynamic scanning canevaluate accurately residuals of viable tumor andnecrosis in HCC lesions.FMPSPGR dynamic contrastscanning is useful in the follow-up of patients with HCCtreated by TACE combined with SE T_1WI and T_2WI,butit is difficult to differentiate peripheral viable tumorsfrom inflammatory infiltration. AIM: To evaluate the role and limitation of fast multiplanar spoiled gradient-recalled(FMPSPGR)MR dynamiccontrast scanning in the follow-up of patients with HCCtreated by transarterial chemoembolization CTACE).METHODS:Twenty-two patients with 24 HCC lesionsconfirmed by biopsy or surgical resection Underwent MR imaging in 4-9wks after TACE with a superconducting1.5 T MR scanner, including SE T_1WI, T_2WI and FMPSPGRdynamic the scanning. The signal intensities of alllesions on SE T_1WI, T_2WI and the enhancement patternson FMPSPGR dynamic contrast scanning were observed, and the The comparison was made between MRI findingsand pathological results in all the cases.RESULTS:Of the 24 lesions,the signal intensities werevarious on SE T_1WI and T_2WI.On T_1WT,13 lesionsappeared as hyperintense,4 lesions were isointenseand the other 7 lesions were hypointensese.Histologically ,Hyperintense lesions showed on T_1WIwere viable tumor or hemorrhage;isointensities werecoagulative necrosis or inflammatory inf Iltration;hypointensities were tumor,liquified necrosis,coagulative necrosis or inflammatory infiltration.OnT_2WI,15 lesions appeared as hyperintense,3 lesionswere isointense and the other 6 lesions werehypointensese.Hyperintense lesions on on T_2WI Were residuals of viable tumor,hemorrhage,liquefied necrosis or inflammatory infiltration;单词interintense lesionswere residuals of viable tumor or inflammatoryinfiltration;hypointense lesions were coagulativenecrosis.On FMPSPGRdynamicdetection,18of the 24 lesions enhanced on early-phase dynamicscanning corresponding to residuals of viable tumor andthe other 6 lesions had no enhancement at this phasebecausecomplete necrosis were seen In the histologic analysis.On delayed-phase dynamic scanning,6lesions had permanent enhancement appeared and both residuals of viable tumor and inflammatory infiltration were found by histologic examination.18 lesions were hypointense at this phase and 8 of them coexistedWith peripheralring-like enhancement of the lesions resulting from viable tumors or inflammatory infiltration.CONCLUSION:FMPSPGR MR dynamic contrast scanningcan reflect the pathologic changes of HCC treated byTACE.Especially,early-phase dynamic scanning canevaluate accurately residuals of viable tumor andnecrosis in HCC lesions.FMPSPGR Dynamic contrastscanning is useful in the follow-up of patients with HCCtreated by TACE combined with SE T_1WI and T_2WI, butit is difficult to differentiate peripheral viable tumors from inflammatory infiltration.