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用放射免疫分析法对８４例急性脑梗塞患者（脑梗塞组）及６０例同龄健康者（对照组）的血浆环磷酸腺苷（ｃＡＭＰ）和环磷酸鸟苷（ｃＧＭＰ）含量进行了测定。结果显示，脑梗塞组血浆ｃＡＭＰ和ｃＧＭＰ含量及其比值均低于对照组，ｃＡＭＰ降低明显（Ｐ＜０．０１），ｃＧＭＰ降低轻微（Ｐ＞０．０５）；其ｃＡＭＰ含量降低及ｃＡＭＰ／ｃＧＭＰ比值减小与病情呈正相关。提示检测血浆ｃＡＭＰ和ｃＧＭＰ含量有助于判断脑梗塞病情，指导脑梗塞的防治
The contents of cAMP and cGMP in 84 patients with acute cerebral infarction (cerebral infarction group) and 60 healthy controls (control group) were determined by radioimmunoassay. The results showed that the levels of cAMP and cGMP in cerebral infarction group were significantly lower than those in control group (P <0.01), the cGMP level was decreased slightly (P> 0.05), the cAMP content and cAMP / cGMP Ratio decreased and the disease was positively correlated. Tip detection of plasma cAMP and cGMP levels help determine the severity of cerebral infarction, and guide the prevention and treatment of cerebral infarction