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卡维地洛引起腹泻卡维地洛(carvedilol)是治疗心衰、心绞痛、高血压及心律失常的药物。新西兰药物不良反应监测中心收到卡维地洛引起腹泻的报告。卡维地洛的常用剂量为6.25-25 mg·d-1。在3个报告中,一周内发生严重腹泻,第4例在用药后1个月内引起中等程度的腹泻。4例停用卡维地洛后腹泻症状改善。已知腹泻为所有β-受体阻断药的ADR。停药时, 必须在2周内逐渐减量撤药,因突然停药可使高血压、心绞
Carvedilol causes diarrhea Carvedilol is a medication for heart failure, angina, hypertension and arrhythmia. The New Zealand Agency for Adverse Drug Reaction Monitoring received a report of carvedilol-induced diarrhea. The usual dose of carvedilol is 6.25-25 mg · d-1. Severe diarrhea occurred in one week in 3 reports and moderate diarrhea in 4 cases within 1 month after treatment. Four patients discontinued carvedilol after diarrhea symptoms improved. Diarrhea is known as ADR for all beta-blockers. Drug withdrawal, must be gradual tapering withdrawal within 2 weeks, due to sudden withdrawal can make high blood pressure, heart rate