Expert’s introductionCarlos Jose Pirola has been a PhD in biochemistry since 1984 (University of Buenos Aires, UBA). He received training in molecular biology in the Cedars Sinai Medical Center in Los Angeles, Califoia, USA. His major interest is Systems Biology of metabolic syndrome components, including hypertension, obesity, type 2 diabetes, and fatty liver. He is currently a senior investigator at the National Scientific and Technical Research Council (CONICET) and is serving both as the chair of the Department of Molecular Genetics and Biology of Complex Diseases and as the director of the Institute of Medical Research (IDIM, UBA-CONICET). He is a member of the American Association for the Study of Liver Diseases (AASLD) and the InterAmerican Society of Hypertension (IASH), being an Inteational Fellow of the American Heart Association (AHA) and The American Society of Human Genetics (ASHG). Dr. Pirola has eaed several national and inteational awards and has more than 170 publication in the PubMed in areas including genetics, epigenetics, metabolomics, and the pathophysiology of cardiometabolic diseases. He was responsible for the creation of the first Center of Excellence in Translational Medicine in Argentina and is serving as a reviewer of a number of inteational jouals including Hepatobiliary Surgery and Nutrition (HBSN) and Annals of Translational Medicine (Figure 1).