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探讨立体定向放疗对肝脏肿瘤治疗的疗效及影响疗效的因素。对１１例肝脏肿瘤患者，２０个肿瘤病灶进行立体定向放疗，肿瘤临床靶体积（ＣＴＶ）为 １．４～１２６．３ ｃｍ３，中位体积是９．５ｃｍ３。给予计划靶体积（ＰＴＶ）边缘剂量为３０Ｇｙ／２～３次，肿瘤中心剂量为ＰＴＶ边缘剂量的１２０％～１５０％。结果表明随访 ３～２７个月，肿瘤局部缓解率为 ８０．０％，ＣＴＶ≤１０ｃｍ３组与ＣＴＶ＞１０ｃｍ３组完全缓解率分别为６３．６％和０％（Ｐ＜０．０１）；３０ Ｇｙ／２次治疗组与３０ Ｇｙ／３次治疗组完全缓解率分别为５０％和２５％（Ｐ＜０．０１）。治疗中及治疗后副反应很小。表明立体定向放疗是一种治疗肝脏肿瘤安全有效的方法，ＣＴＶ≤１０ｃｍ３组和３０ Ｇｙ／２次治疗组的完全缓解率较高。
To investigate the efficacy of stereotactic radiotherapy for liver cancer treatment and the factors that influence the efficacy. In 11 patients with liver tumors, 20 tumors were treated with stereotactic radiotherapy. The tumor’s clinical target volume (CTV) ranged from 1.4 to 126.3 cm3 and the median volume was 9.5 cm3. The planned target volume (PTV) marginal dose was 30 Gy/2 to 3 times, and the center dose of the tumor was 120% to 150% of the PTV marginal dose. The results showed that after 3 to 27 months of follow-up, the local tumor remission rate was 80.0%. The complete remission rates of CTV ≤10cm3 and CTV>10cm3 groups were 63.6% and 0%, respectively (P<0.01); 30 Gy The complete remission rate in the 2 treatment groups and 30 Gy/3 treatment groups was 50% and 25%, respectively (P<0.01). The side effects during and after treatment are small. It shows that stereotactic radiotherapy is a safe and effective method for the treatment of liver tumors. The complete remission rate is higher in the CTV≤10cm3 group and the 30Gy/2 treatment group.