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目的探讨莫沙必利联合胆舒胶囊治疗胆汁反流性胃炎的疗效。方法 183例胆汁反流性胃炎患者随机分成三组,胆舒胶囊组服用胆舒胶囊0.45mg,3次/d;莫沙必利组服用莫沙必利,餐前或餐后5mg/次,3次/d;莫沙必利+胆舒胶囊组,胆舒胶囊0.45mg,3次/d;莫沙必利餐前5mg/次,3次/d。疗程均为6周,采用临床症状总疗效和胃镜结果进行量化评分,计算有效率。结果三组比较莫沙必利+胆舒胶囊组治疗胆汁反流性胃炎有效率高于胆舒胶囊组和莫沙必利组,比较差异均有统计学意义(P均<0.05)。结论莫沙必利+胆舒胶囊组治疗胆汁反流性胃炎起到了协调增强作用,效果明显,多途径阻断BRG的发病机制,治愈率高且无不良反应。
Objective To investigate the efficacy of mosapride combined with biliary fluid in the treatment of bile reflux gastritis. Methods A total of 183 patients with bile reflux gastritis were randomly divided into three groups. The patients in the blessing bladder group were treated with blessing capsule 0.45 mg three times a day, the mosapride group taking mosapride, the pre-meal or postprandial 5 mg, 3 times / d; mosapride + bishu capsule group, biliary capsule 0.45mg, 3 times / d; mosapride 5mg / time before meals, 3 times / d. The course of treatment was 6 weeks, using the total clinical symptoms and gastroscope results to quantify the score, calculate the efficiency. Results The effective rate of the three groups in the treatment of bile reflux gastritis compared with those of the boshu capsule group and the mosapride group was significantly higher than that of the mosapride + boshu capsule group (all P <0.05). Conclusion Mosapride + bishu capsule has a synergistic effect in the treatment of bile reflux gastritis. The effect is obvious, and the mechanism of BRG is blocked in many ways, with high cure rate and no adverse reactions.