我院自1960年以来共收治骨肉瘤76例,其中20例(26%)发生于25岁以上的成年人。在青少年患者肿瘤生长迅速,约86%分布于骨生长活跃的膝部干骺端,放射线表现最常见为硬化或混合型破坏影。成年人骨肉瘤生长缓慢,可散发于身体各部,如颌骨、肩胛骨、跟骨等部。发生于长骨者病变范围可向骨干部蔓延,其放射线征象多为溶骨性破坏影。成年人骨肉瘤常可继发于其它骨病变或骨肿瘤。 Our hospital has treated 76 cases of osteosarcoma since 1960, of which 20 cases (26%) occurred in adults over 25 years of age. In adolescents, tumors grow rapidly, approximately 86% of them are located at the metaphysis of knees where bone growth is active, and radiographic manifestations are most often accompanied by sclerotic or mixed destruction. Adult osteosarcoma grows slowly and can be distributed in various parts of the body such as the jaws, scapula, and calcaneus. The lesions that occur in long bones can spread to the backbone, and most of the radiographic signs are osteolytic lesions. Osteosarcoma in adults is often secondary to other bone lesions or bone tumors.