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鼻咽癌患者与EB病毒有密切关系。其抗体中一种是抗E B V诱导产生的早期抗原复合物扩散成份的抗体〔EA(D)(IgG)〕,另一种是抗EBV壳抗原的抗体〔VCA(IgA)〕。本报告是在美国开展的一项前瞻性研究。共分三组采集血清标本:(1)鼻咽癌组,计151例。〔按世界卫生组织(WHO)的分类法,分为1型,鳞状细胞癌,37例;2型,非角化型癌,18例;3型,未分化型癌,96例。〕(2)病人对照组625例,其中147例头颈部(除鼻咽部外)鳞状细胞癌,71例头颈部其它恶性肿瘤,407例头颈部各种良性疾病患者。(3)健康人对照组278例。全部标本均用间接免疫萤光法做IgG对E A(D)和lgA对
Patients with nasopharyngeal carcinoma and Epstein-Barr virus are closely related. One of the antibodies is an antibody (EA (D) (IgG)) against the diffusion of the early antigen complex produced by E B V and the antibody [VCA (IgA)) against the EBV shell antigen. This report is a prospective study conducted in the United States. Divided into three groups were collected serum samples: (1) nasopharyngeal carcinoma group, accounting for 151 cases. According to the World Health Organization (WHO) classification, divided into type 1, squamous cell carcinoma, 37 cases; type 2, non-keratinized type of cancer, 18 cases; type 3, undifferentiated carcinoma, 96 cases. (2) The patient control group of 625 cases, of which 147 cases of head and neck (except nasopharynx) squamous cell carcinoma, 71 cases of other head and neck cancer, 407 cases of head and neck patients with various benign diseases. (3) 278 healthy controls. All specimens were used for indirect immunofluorescence IgG to E A (D) and lgA pairs