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早期卵巢上皮癌的规范性治疗对预后至关重要。早期卵巢癌要进行全面的分期手术,对于年轻、有生育要求、肿瘤局限于一侧卵巢、任何分级的I期患者,可以保留生育功能。对初次手术分期不全面的患者,应该在化疗开始前进行再分期手术。手术病理分期为Ia和Ib期,高分化患者不必化疗;中分化者可以观察,也可以化疗。所有Ic期、低分化,以及透明细胞癌、癌肉瘤等预后不良的组织病理类型的患者均应进行化疗,疗程3~6个。早期卵巢上皮癌的化疗方案仍以紫杉醇+卡铂方案为最优。化疗前和化疗期间可以使用促性腺激素释放激素类似物进行卵巢保护。
Normative treatment of early ovarian cancer is crucial for prognosis. Early ovarian cancer to conduct a comprehensive staging surgery, for young, fertility requirements, tumor confined to one side of the ovary, any grading of I patients, can retain fertility. Patients with incomplete first stage surgery should be re-staged prior to the start of chemotherapy. Surgical staging for Ia and Ib, well-differentiated patients without chemotherapy; moderate differentiation can be observed, but also chemotherapy. All Ic stage, poorly differentiated, and poor prognosis of clear cell carcinoma, carcinosarcoma and other histopathological types of patients should be chemotherapy, treatment of 3 to 6. Early ovarian cancer chemotherapy regimen is still paclitaxel + carboplatin program for the best. Ovarian protection can be performed with gonadotropin-releasing hormone analogues before and during chemotherapy.