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目的研究壤塘县藏族成人大骨节病膝关节损害患者单次注射玻璃酸钠的疗效和副作用。方法壤塘县藏族成人大骨节病膝关节损害28例,单侧膝关节注射一次玻璃酸钠2.0 ml,注射前及注射后第1、3和8周分别采用VAS疼痛评分、关节活动度和藏区大骨节病日常生活和劳动能力量表评价治疗效果。结果 VAS评分注射前,注射后1、3和8周分别为5.9、3.0、3.2和4.9分;关节活动度增加16°,有效率100%,注射8周后治疗效应开始降低。对日常生活及劳动能力改善不明显。结论膝关节单次玻璃酸钠注射可明显缓解藏族成人大骨节病患者膝关节疼痛,疼痛缓解时间持续2个月。
Objective To study the curative effect and side effects of single injection of sodium hyaluronate in patients with adult Kashin-Beck disease of adult Tibetan in Rangtang County. Methods Twenty-eight adult patients with Kashin-Beck disease in Zangtang County were treated with 2.0 ml sodium hyaluronate once injected into unilateral knee. VAS pain score, joint mobility, District Kashin-Beck disease daily life and ability scale to evaluate the therapeutic effect. Results The VAS score was 5.9, 3.0, 3.2 and 4.9 respectively at 1, 3 and 8 weeks after injection. The VAS score increased by 16 ° and the effective rate was 100%. After 8 weeks of injection, the therapeutic effect began to decrease. Improvement of daily life and working ability is not obvious. Conclusion Single injection of sodium hyaluronate into the knee joint can significantly relieve knee pain in adults with Kashin-Beck disease. The pain relief time lasted for 2 months.