论文部分内容阅读
金剂治疗顽固性支气管哮喘有良效,随着临床上的广泛应用,发生副作用的机会也将增多。本文报告2例金剂所致的肺纤维化及BAL的治疗经验。例1 男性54岁,夜间哮喘3年经金硫葡萄糖注射后,哮喘停止,但用药10个月时(金剂累积量1925mg)出现运动时呼吸困难,胸片发现两肺弥漫性条索状阴影,支气管镜肺活检诊断为肺纤维化,即停药并给类固醇激素每日30mg,10日后合并用BAL治疗。第1天200mg,第2天300mg,第3天后每日100mg,1000mg为一疗程。3疗程后血中金含量明显下降,尿排金量及金的肾清除率显著增加,症状减轻,肺部阴
Bronzing treatment of intractable bronchial asthma have good effect, with the widespread clinical application, the chance of side effects will increase. This article reports 2 cases of bronchitis caused by pulmonary fibrosis and BAL treatment experience. Example 1 Male 54 years old, nighttime asthma 3 years after the injection of gold-sulfur glucose, asthma stopped, but 10 months after administration (gold accumulation 1925mg) appeared dyspnea during exercise, chest radiographs found diffuse bar-like shadow of both lungs Bronchoscopy lung biopsy diagnosed pulmonary fibrosis, that is, withdrawal and steroid hormone daily 30mg, 10 days after the merger with BAL treatment. 200mg on the first day, 300mg on the second day, 100mg on the third day, 1000mg for a course of treatment. 3 after the course of gold blood levels decreased significantly, urinary excretion of gold and gold significantly increased renal clearance, symptoms, lung yin