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对４例输精管注射聚醚型聚氨酯弹性体（ＭＰＵ）栓堵（简称输精管ＭＰＵ栓堵）术后立即切除的栓堵段输精管和１０例输精管ＭＰＵ栓堵术后４年因子女意外或并发症行手术治疗所切除的栓堵段输精管．进行病理形态学观察。结果显示栓堵段输精管全部破裂，大部分ＭＰＵ由破口逸出包裹输精管，管腔内仅存少量ＭＰＵ，术后４年栓堵段输精管管壁不同程度退行性变和纤维组织增生，并伴有玻璃样变和灶性吞噬细胞浸润，栓子两端管腔闭塞。并发痛性结节４例有精了肉芽肿、异物肉芽肿形成，伴神经纤维增生和局部淋巴细胞浸润。并对输精管ＭＰＵ栓堵的机理和手术合并症进行了讨论。
Four cases of accidental or complication of female vas deferens MPU and vas deferens MPU immediately after the operation were removed 4 years after operation. Surgical removal of the plug blocking the vas deferens. Pathological observation. The results showed that the vas deferens blocked and ruptured, most of the MPU escaped from the rupture and wrapped the vas deferens. Only a small amount of MPU was present in the lumen, and the degenerative changes and fibrous tissue hyperplasia of the vas deferens wall were occluded 4 years after operation. Glass-like changes and focal phagocytic infiltration, both ends of the embolization of the lumen occlusion. 4 cases of painful nodules with granuloma, foreign body granuloma formation, with nerve fiber hyperplasia and local lymphocyte infiltration. The mechanism of vasoconstrictor MPU plugging and surgical complications were discussed.