论文部分内容阅读
目的探讨原发性高血压与良性前列腺增生(BPH)发生与进展的相关性。方法对临床明确诊断BPH的195例患者的临床资料,其中95例BPH合并高血压组,100例为单纯BPH患者组。对两组的IPSS评分、血清前列腺特异性抗原(PSA)、前列腺体积、残余尿量及最大尿流率指标进行比较。结果 BPH合并高血压组患者的IPSS评分、PSA和前列腺体积明显大于单纯BPH组(P<0.05)。舒张压≥90 mmHg组患者的前列腺体积大于舒张压<90 mmHg组,有统计学意义(P<0.05);而收缩压≥140 mmHg组与收缩压<140 mmHg组患者各指标比较均无明显差异。与单纯BPH组的各项临床指标相比,BPH合并高血压组中10年以上高血压病史患者的BPH前列腺体积明显增大(P<0.05)。结论 BPH同时合并高血压多见,长期高血压尤其是高舒张压状态能够促进BPH的发生以及临床进展。
Objective To investigate the relationship between essential hypertension and the occurrence and progression of benign prostatic hyperplasia (BPH). Methods The clinical data of 195 patients with clinically definite BPH were analyzed. Among them, 95 patients with BPH complicated with hypertension and 100 patients with pure BPH. IPSS score, serum PSA, prostate volume, residual urine volume and maximum flow rate were compared between the two groups. Results The IPSS score, PSA and prostate volume in BPH patients with hypertension group were significantly higher than those in BPH group (P <0.05). Patients with diastolic blood pressure≥90 mmHg had significantly higher prostate volume than those with diastolic blood pressure <90 mmHg (P <0.05), while no significant difference was found between the systolic blood pressure≥140 mmHg and systolic blood pressure <140 mmHg . BPH group with BPH combined with various clinical indicators, BPH patients with hypertension over 10 years history of BPH prostate volume was significantly increased (P <0.05). Conclusion BPH complicated by hypertension more common, long-term hypertension, especially high diastolic pressure state can promote the occurrence of BPH and clinical progress.