有报道,在多种雄性哺乳类动物,棉酚能引起暂时性的不育,不育的发生率与剂量相关。棉酚引致雄性不育的能力归之于对精子生成的作用和/或对附睾精子的广泛性损伤作用。在人类和实验动物,都只观察到极轻微的副反应。但棉酚的作用存在种属差异,田鼠对棉酚的抗生育作用更敏感,但对其 It has been reported in a variety of male mammals, gossypol can cause temporary infertility, the incidence of infertility and dose-related. The ability of gossypol to induce male sterility is attributed to the effects on spermatogenesis and / or extensive damage to epididymal spermatozoa. In humans and laboratory animals, only very minor side effects were observed. However, the role of gossypol species differences exist, voles are more sensitive to the role of gossypol in fertility, but its