前列腺素(PG)主要由肾髓质、间质、脂质,颗粒所合成,皮质也可合成。这些脂肪酸对于肾脏的血流动力学和水、盐代谢及其它血管活性激素的调节有密切关系。非甾体性消炎药物(NSATD)如消炎痛、布洛芬等可以抑制环氧化酶,从而影响各种前列腺素的生成。本文拟就与临床关系较大的几个重要问题进行讨论。 Prostaglandin (PG) mainly by the medulla, interstitial, lipid, particle synthesis, cortex can be synthesized. These fatty acids are closely related to the hemodynamics of the kidneys and the regulation of water, salt metabolism and other vasoactive hormones. Non-steroidal anti-inflammatory drugs (NSATD) such as indomethacin, ibuprofen and other can inhibit cyclooxygenase, thus affecting a variety of prostaglandin production. This article is intended to be discussed with several major issues of clinical relevance.