妊娠后期及泌乳期添加多潘立酮对经产母猪泌乳性能的影响

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  母猪乳产量是限制新生仔猪生长和猪肉产量的重要因素,而母猪泌乳期采食量高低及体损失大小又共同决定了乳产量的高低。此外,乳汁品质也直接影响新生仔猪泌乳期生长性能及健康状况。多潘立酮(DOM)是一种外周神经多巴胺2型(D2)受体拮抗剂,它能与迷走神经D2受体结合,阻断多巴胺对胃肠道平滑肌的抑制作用,增加上消化道的舒张程度,促进胃排空以及胃肠道蠕动,减少饲料通过胃肠道的时间;同时,DOM能与第四脑室底部的D2受体结合,减小多巴胺对催乳素(PRL)的抑制作用,从而增加腺垂体PRL的分泌。有报道表明,初产母猪妊娠后期添加DOM,可以显著提高血浆PRL浓度,并显著增加泌乳第14天及21天乳产量,从而显著提高仔猪21日龄断奶平均体重。
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