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5. Synthesis and biological evaluation of homoserine lactone derivatives as inhibitors of quorum sensin

Synthesis and biological evaluation of homoserine lactone derivatives as inhibitors of quorum sensin

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：hejianfeng05

【摘 要】

：

The Pseudomonas aeruginosa quorum-sensing(QS)molecule N-(3-oxododecanoyl)-L-homoserine lactone is involved not only in bacterial activation but also in subversion of the host immune system.

【作 者】

：

Xin-Li Chen Kai Zhu Yong-Xi Liang Yue-Ming Jiang Jun-Jie Zhao Chun-Li Wu 

【机 构】

：

School of Pharmaceutical Sciences and New Drug Research & Development Center,Zhengzhou University,Zh

【出 处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

quorum sensing inhibitors synthesis activity 

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　　The Pseudomonas aeruginosa quorum-sensing(QS)molecule N-(3-oxododecanoyl)-L-homoserine lactone is involved not only in bacterial activation but also in subversion of the host immune system.

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