Cellular Mechanisms of Zebrafish Liver Regeneration

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：TORO_123

【摘要】

：

The liver has high regenerative capacity, but it is not clear whether most biliary cells (particularly larger cholangiocytes) transdifferentiate into hepatocytes in regenerating liver.

【作者】

：

Jianbo He Huiqiang Lu Qingliang Zou Lingfei Luo

【机构】

：

Key Laboratory of Freshwater Fish Reproduction and Development, Ministry of Education,Laboratory of

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

Liver damage regeneration biliary transdifferentiation zebrafish model

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The liver has high regenerative capacity, but it is not clear whether most biliary cells (particularly larger cholangiocytes) transdifferentiate into hepatocytes in regenerating liver.

其他文献

Association Among Virulence, Temperature Tolerance and Triadimefon Resistance of Blumeriagraminis f.

Evolution of plant pathogen populations was affected by many factors, such as host resistance,fungicide applying, and environment factors.To explicit the association among virulence,temperature sensit

会议

Cotton HD-ZIP transcription factor GhHB12: a potential negative regulator of JA signaling in defense

Verticillium dahliae is a necrotrophic fungus that causes serious soil-borne vascular disease (Verticillium wilt) in cotton.Previous studies demonstrated that JA signaling plays an important role in c

会议

Physiological and molecular mechanisms of melatonin in innate immunity against bacterial pathogen in

Melatonin is a naturally-occurring small molecule, serving as important secondary messenger in animals.Melatonin has drawn the attention of plant biologists since its discovery in plants in 1995.The f

会议

Unraveling a molecular determinant for clathrin-independent internalization and subsequent degradati

Endocytosis and postendocytic sorting of G-protein-coupled receptors (GPCRs) is of obvious importance for regulation of their cell surface density and the signaling profile.

会议

GPCRmuscarinic acetylcholine receptorsendocytosispost-endocytic traffickings

BMP-mediated canonical and non-canonical signaling in maintaining cardiac functional homeostasis

Heart failure is an end stage disease which can be caused by various pathological insults, such as systemic hypertension, ischemic heart injuries, virus infections, and exposures to reagents with card

会议

Ci通过调节Hippo信号通路的活性来调控果蝇生殖干细胞分化

Hippo信号通路是果蝇以及哺乳动物当中调控器官大小的重要通路。被激活的Hpo通过磷酸化级联反应最终增加Yki的磷酸化，从而阻止Yki入核行使转录因子的功能。通过实验我们发现，当用c587-gal4在果蝇卵巢生殖细胞周围的护卫细胞(EC)中敲低Yki的表达，能够产生生殖细胞过度增殖、延缓分化的表型。我们同时敲低Yki以及其共同作用因子Sd后，能够使这种表型得到回复。所以说Yki的这种表型还是基于经

会议

Hippo信号通路YkiHedgehog信号通路Ci果蝇生殖干细胞Niche

Molecular mechanisms and cellular biophysics of notochord morphogenesis in the basal chordate, marin

Tubular organs support the uptake and exchange of nutrition, metabolites, and gases that are essential for the normal physiology of animals.The notochord of ascidian Ciona forms a tube consisting of o

会议

Marine ascidiansnotochord tubulogenesisactomyosin ringmorphogenetic signaling

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and s

The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor suppressing property.The p53 isoform Δ113p53/Δ133p53 is a p53 target gene that antagonizes p53 apopt

会议

p53 isoform Δ113p53/Δ133p53NHEJHRSSAcell deathsenescence

Tgfβ1a Regulates Zebrafish Posterior Lateral Line Formation via Smad5 Mediated Pathway

The zebrafish sensory posterior lateral line (pLL) has become an attractive model for studying collective cell migration and cell morphogenesis.Recent studies have indicated that chemokine, Wnt/β-cate

会议

zebrafishlateral lineneuromastTgfβ1aSmad5

Identification of Srsf4 as a Novel Target of Androgen Receptor in Mouse Sertoli Cells

The serine/arginine-rich splicing actor 4 (SRSF4) is essential for pre-mRNA splicing and can influence alternative splice site choice, yet little is known about the specific function of this gene in r

会议

Srsf4androgen receptorSertoli cells

Cellular Mechanisms of Zebrafish Liver Regeneration

与本文相关的学术论文