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高度枝化的阳离子聚合物与线型同类相比,有更强的DNA结合能力和更高的转染效率.前期研究发现化合物A可作为开环聚合的原料和不同二胺聚合可得到具有高转染效率的线型聚合物基因载体,对A结构的细微变化会导致转染效率大大降低.
通过环氧开环聚合的高枝化阳离子聚合物基因转染载体
【摘 要】
：
高度枝化的阳离子聚合物与线型同类相比,有更强的DNA结合能力和更高的转染效率.前期研究发现化合物A可作为开环聚合的原料和不同二胺聚合可得到具有高转染效率的线型聚合物基因载体,对A结构的细微变化会导致转染效率大大降低.
【机 构】
：
四川大学化学学院,绿色化学与技术教育部重点实验室 四川省成都市望江路29号,610064
【出 处】
：
第八届全国化学生物学学术会议
【发表日期】
：
2013年2期
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