Group-Combined P-value with Applications to Genetic Association Studies

来源 :中国现场统计研究会 | 被引量 : 0次 | 上传用户:qjunp
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Combined p-value is widely used in genetic association analysis to detect the connections between multiple locations of genetic mutation and complex diseases.
其他文献
In this paper,we consider the Stein-Type approach to the estimation of the regression parameter in a multiple regression model under a multicollinearity situation.
会议
We present a new framework on structural similarities and differences between multiple high-dimensional Gaussian graphical models(GGMs)over a set of nodes under distinct experimental conditions.
会议
Feature screening is an important technique in preliminary regression analysis with ultrahigh dimensional predictors.
会议
We investigate the problem of estimating the Cholesky decomposition in a conditional independent normal model with missing data.
会议
This paper studies the asymptotic properties of the adaptive elastic net in ultra-high dimensional sparse linear regression models and proposes a new method called SSLS(Separate Selection from Least S
会议
In recent years,effective monitoring of data quality has increasingly attracted attention of researchers in the area of statistical process control(SPC).
会议
基于相对剥夺理论,重新定义了基尼系数子群之间不平等的表达式,随后选取若干经济指标,将我国19个行业分为4类,通过基尼系数子群分解,测算全国行业收入差距基尼系数,以及群间和群内不平等对基尼系数的贡献,发现我国行业收入差距子群之间的不平等较为明显,其中第一个子群即民生服务产业相对于其他三个行业表现出明显相对剥夺感;第二子群即高新技术产业相对其他三个子群表现出明显的优越性,通过计算和比较不同地区行业收入
现代统计学习中的核方法通过某种非线性映射将原始数据嵌入到合适的高维特征空间;然后,利用通用的线性学习器在这个新的空间中分析和处理模式,核方法在生物化学领域已经获得了广泛的应用。在生物学中,SMILES是一种用ASCII字符串明确描述分子结构的规范。
会议
We propose a new class of space-filling designs called rotated sphere packing designs for computer experiments.