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5. Synthesis and evaluations of three folate analogue-lipid conjugates as the targeting materials for t

Synthesis and evaluations of three folate analogue-lipid conjugates as the targeting materials for t

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：jakey17866747

【摘 要】

：

Objective: Specific binding between ligand and receptor is used as a targeting strategy to enhance the accumulation of drug-loaded liposomes in the cancer tissues.Folate receptor has been found to be

【作 者】

：

Rui-Jun Ju Wan-Liang Lu 

【机 构】

：

School of Pharmaceutical Sciences,Peking University,Beijing,China,100191

【出 处】

：

2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会

【发表日期】

：

2014年8期

【关键词】

：

Folate analogue-lipid conjugates targeting materials invasive breast cancer 

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Objective: Specific binding between ligand and receptor is used as a targeting strategy to enhance the accumulation of drug-loaded liposomes in the cancer tissues.Folate receptor has been found to be overexpressed on invasive breast cancer cells.

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