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5. The mechanism of Histone lysine-specific demethylase 1 regulating TGF-β1 expression in gastric epith

The mechanism of Histone lysine-specific demethylase 1 regulating TGF-β1 expression in gastric epith

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：hzj123456789

【摘 要】

：

Lysine specific demethylase 1(LSD1),the first identified histone lysine demethylase by Yang Shi group in 2004[1],specifically catalyzes demethylation of mono-and di-methylated lysine 4 and lysine 9 of

【作 者】

：

Jin-Feng Li Zhi-Ru Wang Jin-Lian Ma Yi-Chao Zheng Chun-yang Wang Wen Zhao Hong-Min Liu 

【机 构】

：

New Drug Research & Development Center,School of Pharmaceutical Sciences,Zhengzhou University,100 Ke

【出 处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

LSD1 TGF-β1 ChIP GES-1 

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　　Lysine specific demethylase 1(LSD1),the first identified histone lysine demethylase by Yang Shi group in 2004[1],specifically catalyzes demethylation of mono-and di-methylated lysine 4 and lysine 9 of histone 3,key chromatin marks associated with transcriptional activation and repression[2].

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