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Chemokine CCL24 is the second member of eotaxins,a group of eosinophilsselectively chemoattractants.Via binding to its only receptor CCR3,CCL24 mainly mediates atopic disorders,parasitic infections and systemic diseases.It is well-known that CCR3 is expressed at the maternal-fetal interface;nevertheless whether CCL24 is located there and which role CCL24/CCR3 axis played is unclear.In this article,we assessed the expression of CCL24 and CCR3 in decidual stromal cells (DSCs) and trophoblasts,investigated the effects of DSCs-trophoblasts contact and pregnancyassociated hormones on the expression of CCR3 by DSCs,and last examined the role of trophoblasts-derived CCL24 on the proliferation,cell numbers and apoptosis of DSCs in vitro.