【摘 要】
：
We evaluated differences in biopsy-detected prostate cancer (PC) between a newly defined Korean clinical cohort (KCC) and two Western populations.The records of 723 Korean men aged 55 to 75 years who
【机 构】
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Korea University Medical Center
【出 处】
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第十三届亚洲泌尿外科学会年会(UAA2015)、第二十二届全国泌尿外科学术会议(CUA2015)、第十六届全军及武警泌尿
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We evaluated differences in biopsy-detected prostate cancer (PC) between a newly defined Korean clinical cohort (KCC) and two Western populations.The records of 723 Korean men aged 55 to 75 years who underwent an initial transrectal ultrasound-guided biopsy from 2004 to 2010 were retrospectively reviewed.Prostate biopsies were performed due to prostate-specific antigen (PSA) levels greater than 4.0 ng/ml, or suspicious findings on rectal examination or transrectal ultrasonography.Characteristics of PC were compared between the KCC and Western groups.The cancer detection rate was 26.4％ (191/723) in the KCC, 20.9％ (473/2268) in the ERSPC/Rotterdam group and 43.1％ (138/320) in the DCC.The median PSA in patients with PC was 11.8 ng/mL, 5.7 ng/mL and 7.5 ng/mL in the KCC, ERSPC/Rotterdam group, and DCC, respectively.The proportion of patients with a Gleason score of 7 or more was 57.1％ (109/191) in the KCC, 37.5％ (174/464) in the ERSPC/Rotterdam group and 37.0％ (51/138) in the DCC.We found large differences in cancer detection rate, PSA, and Gleason score distribution between the KCC and Western cohorts.PC is detected at more advanced stages in Korean patients than in Western populations due to low availability of PSA screening programs.
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