超声引导下前列腺穿刺活检结果的预测--首项基于大样本量中国人群的列线图研究

来源 :第十三届亚洲泌尿外科学会年会(UAA2015)、第二十二届全国泌尿外科学术会议(CUA2015)、第十六届全军及武警泌尿 | 被引量 : 0次 | 上传用户:lvbei2008
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目的:目前所建立的预测前列腺穿刺的模型均基于欧美人群,且缺乏影像学预测价值的分析.基于大样本量的中国患者人群,本研究致力于建立预测超声引导下前列腺穿刺活检结局的列线图(nomogram),并评估前列腺核磁共振(MRI)等指标对于前列腺癌的诊断价值.方法:回顾性分析于2011年1月至2013年11月间于北京大学第一医院泌尿外科行超声引导下前列腺穿刺活检的954例患者.已排除穿刺前未行前列腺核磁检查、PSA>100ng/ml、前列腺体积>150ml、无完整临床病理信息的患者.所有患者MRI均经三名影像学医师再次评估,综合考虑PI-RADS评分和临床应用,划分为阳性(PI-RADS 4-5分)、可疑(PI-RADS 3分)、阴性(PI-RADS l-2分)三种评价.采用R软件建立预测前列腺癌(PCa)和高级别前列腺癌(HGPCa,Gleason Score≥7分)的列线图.
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