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5. The Synthesis and Biological Properties of C4'-CF3 Modified Ribonucleotides

The Synthesis and Biological Properties of C4'-CF3 Modified Ribonucleotides

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：shijunjie88

【摘 要】

：

Due to the specific properties of fluorine atom,such as small size,high electronegativity,carbon-fluorine bone strength and sensitivity of 19F NMR,the introduction of fluorine atom(s)into biomolecules

【作 者】

：

Fengmin Guo Zhen Xi Chuanzheng Zhou 

【机 构】

：

State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical Biology,College of Che

【出 处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年10期

【关键词】

：

Synthesis Fluorinated nucletides Biological properties 

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　　Due to the specific properties of fluorine atom,such as small size,high electronegativity,carbon-fluorine bone strength and sensitivity of 19F NMR,the introduction of fluorine atom(s)into biomolecules can bring about remarkable and profound physical,chemical and biological properties.

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