Preconditioning with recombinant HMGB1 induces ischemic tolerance in a rat model of focal cerebral i

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户:ZXYCHENLI
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  Preconditioning means that a previous minor insult prepares the body to better withstand a subsequent larger insult.High mobility group box 1(HMGB1)is a reported that mediates High mobility group box 1(HMGB1)is a reported that mediates the response to infection,inflammatory and injury.
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Background and Purpose We aimed to investigate whether NADPH oxidase,a major ROS-producing enzyme,was involved in the antioxidant effect of acupuncture on cognitive impairment after cerebral ischemia.
Objective Our previous studies have demonstrated that limb ischemic preconditioning(LIP)induced brain ischemic tolerance and up-regulated the expression of p38 MAPK and ERK in hippocampal CA1 region i
Diabetes mellitus(DM)is a group of metabolic disease with symptoms of high blood sugar levels,which may worse the stroke caused injury under unclear mechanisms.
会议
To define the factors responsible for ischemia-induced blood-brain barrier damage is first necessary before a new strategy can be developed to counter the adverse effect of ischemia-induced endothelia