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  5. Computing the Phenotype Similarity Based on OMIM Database and MESH Vocabulary

Computing the Phenotype Similarity Based on OMIM Database and MESH Vocabulary

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：cwfml9
【摘 要】
：
Background: According to genetics, similar set of genes may affect the similar phenotypes, and the similar phenotypes may be caused by a set of similar genes.So when we know the relevant genes of a ph
【作 者】
：
Xinhua Liu Xia Li Meng Liu Rui Fan Yanshi Hu Ying Hu Xianfu Yi Tao Zhang Ju Wang 
【机 构】
：
School of Biomedical Engineering, Tianjin Medical University, Tianjin 300070, China
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
OMIM database MESH vocabulary phenotype nicotine addiction 
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　　Background: According to genetics, similar set of genes may affect the similar phenotypes, and the similar phenotypes may be caused by a set of similar genes.So when we know the relevant genes of a phenotype, we may be able to infer the genetic characteristics of phenotypes similar to it.So, measuring the similarity between different phenotypes is important in the study of complex physiological process, especially for complex diseases.However, there are few studies to compare the similarity between phenotypes.
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