CAMKII-DEPENDENT TROPONIN-I PHOSPHORYLATION CONTRIBUTES TO THE FREQUENCY-DEPENDENT ACCELERATION OF R

来源 :第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int | 被引量 : 0次 | 上传用户：meheaven

【摘要】

：

【作者】

：

Wang Yanggan Amaud Guilbert Hyun Joung Lim Jun Cheng Catherine Passariello

【机构】

：

Department of Cardiology,Zhongnan Hospital of Wuhan University

【出处】

：

第二十四届长城国际心脏病学会议、亚太心脏大会暨国际心血管病预防与康复会议(The 24th Great Wall Int

【发表日期】

：

2013年2期

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Objectives Frequency-dependent acceleration of relaxation (FDAR) is an intrinsic mechanism in ventricular myocytes allowing a faster ventricular relaxation (and diastolic filling) at fast heart rates.Previous studies suggest that CaMKII activity is required for FDAR but the molecular targets remain elusive.

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CAMKII-DEPENDENT TROPONIN-I PHOSPHORYLATION CONTRIBUTES TO THE FREQUENCY-DEPENDENT ACCELERATION OF R

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