【目的】分析部分性发作癫痫患儿智力发育状况,研究影响部分性发作癫痫患儿智力发育的独立影响因素。【方法】对根据症候学、EEG及MRI检查等检查结果诊断为部分性发作的106例癫痫患儿进行智商测定,根据智商测定结果将患儿分为智力正常组(IQ≥80)和智力异常组(IQ<80)。经单因素和多因素Logistic回归分析确定影响部分性发作癫痫患儿智力发育的因素。【结果】Logistic回归分析发现:首发年龄(P=0.000,OR=6.348,95%CI:2.290～17.599),发作频率(P=0.017,OR=3.479,95%CI:1.250～9.684),MRI检查结果(P=0.004,OR=4.849,95%CI:1.654～14.212),发作类型(P=0.011,OR=3.527,95%CI:1.330～9.349),服用抗癫痫药物量(P=0.012,OR=3.862,95%CI:1.341～11.124)为部分性发作癫痫患儿智力发育的独立影响因素。病程、年龄等因素与智力发育没有显著性关系。【结论】首发年龄小、发作频率高、MRI阳性、发作类型为继发全面性发作、服用抗癫痫药物量大的部分性发作癫痫患儿智力发育更容易受损。 【Objective】 To analyze the mental development of children with partial seizures and to study the independent influencing factors of mental development in children with seizures. 【Methods】 106 children with epilepsy who were diagnosed as partial seizures on the basis of the results of symptomology, EEG and MRI examination were measured with IQ. According to the result of IQ test, children were divided into two groups: normal intelligence group (IQ≥80) and intelligence abnormality Group (IQ <80). Single factor and multivariate Logistic regression analysis to determine the factors that affect the intellectual development of children with partial seizures. 【Results】 The Logistic regression analysis showed that the onset age (P = 0.000, OR = 6.348, 95% CI: 2.290-17.599), frequency of seizure (P = 0.017, OR = 3.479, 95% CI 1.250-9.684) (P = 0.004, OR = 4.849, 95% CI: 1.654-14.212), seizure type (P = 0.011, OR = 3.527, 95% CI: 1.330-9.349) = 3.862, 95% CI: 1.341 ~ 11.124) were independent influencing factors of intellectual development in children with partial seizures. The course of disease, age and other factors and mental development have no significant relationship. 【Conclusion】 The onset age is small, the seizure frequency is high, the MRI is positive and the type of seizure is secondary to full-blown seizures. The mental development of children with partial seizures and epilepsy is more likely to be impaired.