reduction-sensitive相关论文
Bioreducible micelles self-assembled from reduction-sensitive hyaluronic acid-deoxycholic acid conju
Reduction-sensitive polymers and conjugates have emerged as a fascinating class of biomedical materials that can be eleg......
Drug delivery systems (DDS) have appeared as a promising and reliable approach to delivering potent drugs to the site of......
Anisamide-functionalized intelligent polymersomes mediate targeted delivery of methotrexate into lun
Polymersomes are one of the most ideal systems for intracellular delivery of water-soluble apoptotic drugs including low......
Apoptotic proteins possess high anticancer activity,however,their clinical use is hampered by the absence of a suitable ......
Highly efficacious and targeted chemotherapy of human lung cancer by α3β1 integrin specific,redox-re
Cancer nanomedicines have promised to offer a better treatment for human malignancies[1-2].Pegylated liposomal doxorubic......
Reduction-sensitive injectable hyperbranched polyphosphoramidate-hyaluronan hybrid hydrogels for con
Presently,hydrogels are widely used for controlled drug delivery,due to their tunable chemical and physical structure,hi......
Interface crosslinked poly(ethylene glycoi)-poly(amino acid)s copolymer micelles for reduction-trigg
Polymeric micelles self-assembled from amphiphilic block polymers have been widely used for drug delivery.However,a prac......
Novel reversibly crosslinked chimaeric polypeptide polymersomes for active loading and intracellular
The disulfide-crosslinking approach has shown to elegantly resolve the extracellular stability and intracellular drug re......
Reduction-sensitive micelles with detachable poly (2-ethyl-2-oxazoline) corona for enhanced intracel
Micelles formed from poly (ethylene glycol) (PEG) conjugates through self-assembly have been widely studied for delivery......
Reduction-sensitive nanogels based on HA and iodixanol for both tumor-targeted CT imaging and therap
In recent years,nanosized CT contrast agents have attracted great interest as they have several advantages over small mo......
Mesoporous silica nanoparticles (MSNs) have evidenced to be an effective drug delivery system[1].It is well documented t......
Camptothecin-conjugated biodegradable prodrug micelles for theranostic near-infrared fluorescent ima
Camptothecin(CPT) has shown significant antitumor activity in a broad spectrum of human malignancies.However,its use is ......
Co-delivery of doxorubicin and triptolide with reduction-sensitive lipid-polymer hybrid nanoparticle
Co-delivery is a promising strategy to overcome the limitations of single chemotherapeutic agent in cancer treatment.Des......
Reversibly disulfide-crosslinked pullulan nanoparticles for dual-targeted and biotriggered anti-tumo
Biodegradable polymeric nanosystems are among the most promising platforms for delivery of lipophilic drugs.However,low ......
Synthesis and characterization of low-density lipoprotein modified poly-N-succinyl chitosan lipoic a
Objective: In this paper, we report on reduction and pH dual-sensitive reversibly core-crosslinked micelles based on N-s......
基于肿瘤细胞内外还原性环境而设计合成还原敏感型肿瘤靶向药物得到人们的关注。小分子药物在偶联时由于化学结构发生改变,导致药......
Celastrol,a Chinese herbal medicine,has exhibited anticancer activity in many types of cancer cells.However,the further ......
以聚ε-己内酯二元醇(PCL)为软段,赖氨酸二异氰酸酯(LDI)和胱胺(cystamine)为硬段,合成了以胱胺封端的线性聚氨酯预聚体,然后利用......
