heroin相关论文
Activation of serotonin 5-HT2C receptor suppresses behavioral sensitization and naloxone-precipitate
Heroin dependence is a chronic relapsing disorder characterized by persistent and compulsive drug-seeking and –taking b......
Rationale The mesolimbic dopamine system has been proved to be the key neural substrates underlying the rewarding effect......
Glutamatergic projections from entorhinal cortex to dorsal dentate gyrus mediate context-induced rei
Objective Re-exposure to the context associated with heroin intake provokes relapse to drug in addicts after abstinence,......
Recent research in both animals and humans has indicated that deep brain stimulation(DBS) may have potential for the tre......
Improvement of depression-like behavior in rat by memantine prevents heroin seeking after withdrawal
Objectives The aim of the present study was to determine a role of memantine in heroin withdrawal-nduced depression-like......
Introduction: Exosomes are small membrane vesicles abundant in plasma.Exosomes are important in cell-to-cell communicati......
Improvement of depression-like behavior in rats by memantine prevents heroin seeking after withdrawa
OBJECTIVE Depression is the key symptoms in anhedonia after heroin withdrawal and also is often the main cause for recur......
Memantine attenuates reinstatement of heroin seeking induced by heroin or cues in an animal model of
OBJECTIVE To study the effects of acute treatment with memantine on the heroin seeking behavior.MEHTODS Rats were self-a......
Significant association of rs17189632 in the glutamate receptor subunit gene (GRIN3A) with heroin de
OBJECTIVE The N-methyl-D-aspartate receptor is consisting of three subfamilies (NR1, NR2A,2B, 2C, 2Dand NR3A, 3B).The ab......
ROLE OF GLUTAMATERGIC PROJECTIONS FROM THE ENTORHINAL CORTEX TO THE DENTATE GYRUS IN CONTEXT-INDUCED
Exposure to the environmental contexts associated with heroin intake can provoke relapse to drug abuse in addicts after ......
Brain-derived neurotrophic factor serum levels in heroin-dependent patients after 26 weeks of withdr
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of heroin dependence.BDNF expression......
The new challenge of harm reduction organization faced due to the changes in drug use pattern of her
The changes of the injecting drug users (IDU) from using heroin to methamphetamine have been drawing increasing attentio......
Immediate Psychological Effects, Short-and Medium-term Behavioral Effects of Motivation-Skills-Desen
Aim To evaluate the efficacy of the Motivation-Skills-Desensitization-mental Energy Model inpsychological rehabilitation......
Rolipram inhibits the heroin-seeking behavior induced by heroin priming or heroin-associated conditi
Objective Several lines of evidence have suggested a critical role for CREB activities, which activated by changes of cA......
Interaction between dopaminergic and cholinergic transmission in the nucleus accumben mediates the h
The mesolimbic dopamine system projects from VTA to the nucles accumbens (NAc) and is a key neural substrate regulating ......
"ICE" (crystal methamphetamine) is among the most commonly abused drugs in the 21 st century.Research has indicated th......
给出海洛因和鸦片的傅里叶红外吸收实测谱。根据吸收峰的位置,计算出海洛因的基本声子能量:ELO=0.0486 eV,ETO1=0.0555 eV,ETO2=0.......
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Abnormal function of the posterior cingulate cortex in heroin addicted users during resting-state an
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目的 观察海洛因戒断、复吸对大鼠脑VTA、NAc神经元表达酪氨酸羟化酶(TH)和多巴胺β羟化酶(DβH)的影响,探讨多巴胺(DA)和去甲肾上......
目的:探讨立体定向毁损术治疗海洛因依赖的手术方法并评估其手术疗效.方法:应用PET、fMRI和多排螺旋CT及手术计划系统进行靶点定位......
目的 采用2种基数估计方法对广东省6个地区的吸毒人群规模进行估计,力图找到一种经济、方便、快捷和相对准确的基数估计方法.方法 ......
目的:以Sprague Dawley (SD)大鼠为实验对象,明确海洛因急慢性给药对大鼠的中脑腹侧被盖区(ventral tegmental area,VTA)中孤儿核......
目的通过慢性海洛因给药分析杏仁核内Sirt家族表达变化，筛选在海洛因给药后具有显著表达改变的目标分子，继而干预杏仁核内目标分子Si......
Drug abuse has spread quickly since reemerging as a national problem in China in the late 1980s. The number of registere......
,Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior i
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Drug abuse has a long, but also different history in Germany and China. The Opium War largely influenced the history of ......
,Initial experience of heroin use under a two-chained operant schedule influences drug-seeking behav
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目的观察边缘下皮质(IL)脑区注射β2肾上腺素受体激动剂克仑特罗对海洛因自身给药大鼠复吸行为的影响。方法成年雄性SD大鼠采用固......
目的在建立大鼠海洛因辨别刺激模型基础上，评估不同浓度的尼古丁对海洛因辨别刺激的替代作用。方法采用固定比率食物强化方法训练雄......
目的探讨海洛因依赖者和戒断者背侧注意网络(DAN)的功能影像学变化及其对注意功能的影响。方法17例海洛因依赖者和15例海洛因戒断......
目的:考察不同戒断期海洛因戒断者对药物相关刺激认知加工偏向的损伤与恢复情况.方法:研究分别记录控制组、短期、中期和长期戒断......
To observe the effect of electro-acupuncture on the relapse to heroin-seeking induced by heroin-related cues after withd......
Abnormal function of the posterior cingulate cortex in heroin addicted users during resting-state an
Background Previous animal and neuroimaging studies have demonstrated that brain function in heroin addicted users is im......
目的探讨在大鼠海洛因戒断、脱毒治疗和复吸期间,胰岛淀粉样多肽(IAPP)和葡萄糖转运蛋白2(GLUT2)在胰岛β细胞内表达的变化。方法......
目的 探讨油橄榄叶提取物(OLE)对海洛因依赖小鼠认知和氧化损伤及细胞凋亡的影响.方法 150只小鼠皮下注射海洛因(10 mg/kg)40 d,再......
目的 探讨海洛因对小鼠视网膜结构的影响.方法 60只昆明小鼠随机分为对照组和海洛因组2组,海洛因组用递增剂量(2,3,4 g/L)连续(1～5......
目的 探讨海洛因依赖者认知功能受损与血清一氧化氮(NO)等的关系.方法 运用韦氏记忆量表(WMS)、数字划销测验(NCT)、威斯康星卡片......
目的阐述海洛因所致海绵状白质脑病的MR影像学表现及其诊断价值.方法收集11例具有吸食海洛因病史患者的MR影像资料.所有患者均进行......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的 观察海洛因成瘾者和健康被试接受传统针刺和电针治疗时功能性脑区的激活差异.方法 采用功能性核磁共振成像技术,分别对健康被......
目的 采用海洛因依赖大鼠模型来探讨海洛因成瘾对大鼠背侧和腹侧海马痛觉调制的影响.方法 按剂量逐日递增原则,1日2次,连续9d皮下......
目的 建立大鼠海洛因成瘾易感性差异模型,探讨其可能的前额叶皮质D2受体(D2R)及多巴胺转运体(DAT)机制.方法 130只雄性SD大鼠随机......
In order to develop the heroin abstainers cue-sensitization questionnaire (HACSQ),and evaluate its reliability and valid......
目的 探讨海洛因和麻黄素对仔鼠下丘脑、海马组织结构及胆碱乙酰基转移酶(ChAT)活性的影响,观察Bax蛋白和角质细胞生长因子(KGF)在......
Simultaneous Determination of Heroin, Amphetamine and their Basic Impurities and Adulterants Using M
Simultaneous separation of 17 species of heroin, amphetamine and their basic impurities and adulterants was conducted wi......
背景:半胱-天冬氨酸蛋白酶8(Caspase-8)是细胞凋亡过程起始的重要因子,二乙酰吗啡可致神经元细胞凋亡,其与二乙酰吗啡致小脑颗粒神......
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目的采用超高效液相色谱-串联四极杆质谱仪(UPLC-MS/MS),在电喷雾离子源正离子(ESI+)和多反应监测(MRM)模式下建立了定性、定量测......
