deubiquitination相关论文
Objective A number of guanine nucleotide exchange factors(GEFs)including cell transforming factor ECT2 are believed to d......
The tumor suppressor CYLD contains three cytoskeleton-associated protein glycine-rich (CAP-Gly) domains in the amino ter......
Aims: The Maf family proteins belong to the basic leucine zipper transcription factors,including c-fos andc-jun.The tran......
Ubiquitin-specific protease 4 (USP4) positively regulates RIG-I signaling through deubiquitination a
Retinoic acid-inducible gene I (RIG-I) is a major cytosolic RNA sensor to detect RNA virus and initiate the antiviral in......
Discovery of [1,2,3]triazolo[4,5-d]pyrimidine derivatives as highly potent, selective, and cellularl
Ubiquitin specific peptidase 28 (USP28) is closely associated to the occurrence and development of various malignancies,......
Hepatitis B virus(HBV)is regarded as a stealth virus,invading and replicating efficiently in human liver undetected by h......
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Maintenance of cell junctions plays a crucial role in the regulation of cellular functions including cell proliferation,......
泛素化是一种广泛存在且非常重要的可逆的蛋白质翻译后修饰,在蛋白质的稳定性、活性、细胞内定位以及免疫系统的调控过程中发挥了......
去泛素化酶具有逆转泛素化的作用，其大多数研究还保留在分子生物学领域，在转化医学研究中尚未引起充分的重视。目前研究发现，去泛素化......
PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interfe
由象严重急性呼吸症候群(SARS ) 那样的 coronaviruses 的感染 coronavirus (SCoV ) 和老鼠肝炎病毒 A59 (MHV-A59 ) 导致很小的类......
病毒的感染开始激活抄写因素的一系列发信号的串联原子因素 kappa B 和干扰素规章的因素 3，它协作为类型导致基因的抄写我干扰素(IF......
目的：探讨去泛素化酶Rpn11蛋白在套细胞淋巴瘤（MCL）中的表达及其临床病理意义。方法：收集20例初治MCL的标本及资料,以10例反应性增生淋......
