TOXICOLOGY相关论文
王氏保赤丸是一个具有180多年应用历史的中药复方.本研究利用大鼠给药模型,对王氏保赤丸的临床前安全性进行了研究.在28天的给药实......
Rhododendron molle G.Don,belonging to the Ericaceae family,is a traditional Chinese medicinal plant with a wide spectrum......
Proteomic analysis of hepatic protein profile in rare minnow (Gobiocypris rarus) exposed to pentachl
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Objective: The research made detoxification of rapeseed peptides by using dual frequency ultrasound assisted technology.......
Objective: Nanotechnology has emerged as an exciting and promising means of treating CNS related disease,with the potent......
Graphene and its derivatives are new carbon nanomaterials with the prospect for great applications in electronics,energy......
“十八反”是中药组方（禁忌）理论的重要组成部分。针对近十年来 进行的大量的十八反的研究工作，本文从物质基础、药效、毒理、药物代 ......
Towards a better understanding of therapeutic potential of Rhizoma Alismatis:A review on ethnomedici
Rhizoma Alismatis(RA),the dried rhizome of Alisma orientalis(Sam.)Juzep,is a widely used traditional herbal medicine pop......
The present paper aims to provide an up-to-date review at the advancements of the investigations on the ethnopharmacolog......
Silica nanoparticles (SiNPs) play a vital role in medicine applications such as drug delivery and cancer therapy.SiNPs c......
Tripterygium wilfordii Hook.f.has a long history of use in traditional Chinese herbal medicine.It is used for the treatm......
Monitoring and assessing the effects of contaminants in the aquatic environment is critical to protect human health and ......
ROBUST RIDGE REGRESSION ESTIMATORS FOR NONLINEAR MODELS WITH APPLICATIONS TO HIGH THROUGHPUT SCREENI
Nonlinear regression is often used to evaluate the toxicity of a chemical or a drug by fitting data from a dose-response......
Inhibitory Effect of Short and Long-term Administration of Tea Polyphenols on +Gz Induced Lipid Pero
ObjectiveTo observe the effect of short and long-term administration of tea polyphenols（TP） on +Gz induced peroxidative in......
Oleanolic acid(OA)is a pentacyclic triterpenoid chemical component that exists in natural plants with a molecular formul......
Salvia miltiorrhiza Bunge,known as red sage or Danshen,is commonly applied in Chinese herbal therapeutics for various bi......
Biological Activity Relationship of Cyclic and Noncyclic Alkanes Using Quantum Molecular Descriptors
A 3-Dimension-Quantitative Structure-Activity Relationship</span></span><span><span><span style=“font-family:”“> (</s......
Fingerprinting fecal DNA and mRNA as a non-invasive strategy to assess the impact of polychlorinated
In toxicological studies,experimental animals are generally subjected to dissection to obtain the tissues of concern,whi......
High-efficient zebrafish(embryo)handling platforms are crucially needed to facilitate the deciphering of the increas......
Pesticides are extensively used around the world and pesticide toxicity has become a serious threat to human health ......
1H NMR-Based Metabolomics Study on Repeat Dose Toxicity of Fine Particulate Matter in Rats after Int
Systemic metabolic effects and toxicity mechanisms of ambient fine particulate matter(PM2.5)remain uncertain.In orde......
The research method on carcinogenesis mechanisms of cigarette smoke condensate based on network toxi
Aim: To create a research method on carcinogenesis mechanisms of cigarette smoke condensate (CSC) based on network toxic......
Plasmid DNA assay is a newly-developed in vitro method to investigate bioreactivity of particles. In this paper, this me......
目的 评价赶黄草的食用安全性.方法 依据食品安全性毒理学评价程序和方法进行大、小鼠急性经口毒性试验、遗传毒性试验(Ames试验、......
长链非编码RNA(long non-coding RNA,lncRNA)是一类转录本长度超过200个核苷酸、不具有编码蛋白质潜能的RNA.近年来,lncRNA受到广......
Traditional Chinese medicine of SalviamiltiorrhizaBunge:a review of phytochemistry, pharmacology and
Salvia miltiorrhiza Bunge, known as red sage or Danshen, is commonly applied in Chinese herbal therapeutics for various ......
目的 对人工气管的相关组分材料进行毒理学评价实验.方法 本实验按照国际国内既定标准,对纳米碳纤维、胶原蛋白-纳米羟基磷灰石等......
目的:观察慢性毒理试验中,密蒙花颗粒剂对实验大鼠全身组织器官病理组织切片的影响。方法:取80只SPF级SD大鼠,雌雄各半,随机分为4......
小型猪在解剖、生理、生化等方面与人具有很高的相似性,国外采用小型猪用于药物安全性评价的实验研究越来越多.但是,由于背景数据......
随着儿童用药的安全性日渐引起人们的重视,我国国家食品药品监督管理总局提倡用幼年大鼠评价儿童药物非临床研究,更能充分暴露儿童......
丙烯酰胺是较常见的化工原料,对人体神经系统危害很大。本文从丙烯酰胺的代谢动力学研究和不同剂量率的作用特点以及毒理学特征进......
目的 通过大鼠28天喂养试验观察测试某牌号参茶的亚急性毒性.了解参茶对大鼠各项指标的影响,检验其安全性.方法 按照《食品安全国......
Low concentrations of atrazine,glyphosate,2,4-dichlorophenoxyacetic acid,and triadimefon exposures h
Many chemicals are released into the environment,and chemical contamination has been suggested as a contributing factor ......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
本文回顾了国外航天环境毒理学的典型研究成果,对我国载人航天20年发展过程中,航天环境毒理学的研究成果进行了总结,系统阐述了航......
推进剂中的纳米材料主要是指利用纳米技术制造的具有纳米尺寸用于提高推进剂推进性能的材料,包括单一金属粉、复合金属粉、氧化物......
Taxonomical outlines of bio-diversity of Karnataka in a 14th century Kannada toxicology text Khagend
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
The evolutionarily unique and ecologically diverse family Conidae presents fundamental opportunities for marine pharmaco......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Many species of genus Bupleurum L.have been pharmaceutically used mainly in Asia and Europe for thousand years.Their roo......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
The acute (12 h) and chronic (7 or 14 d) effects of tributyltin chloride (TBT) on a new type of test fish, the Chinese r......
Possible Role of DNA Polymerase beta in Protecting Human Bronchial Epithelial Cells Against Cytotoxi
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
神经损伤为区域神经阻滞的常见并发症,尽管新型酰胺类长效局麻药左旋布比卡因、罗哌卡因的应用增多,布比卡因逐渐减少,但目前尚无......
食品中的氯丙醇污染是目前国际上广为关注的食品安全问题之一,最初在酸水解植物蛋白加工中被检出,近年来发现氯丙醇及其酯类化合物......
在M 550毒性研究之一的基础上进一步做亚慢性皮肤毒性试验 ( 90d) ,以了解M 550在较长时间内 ,少量、多次、反复作用下 ,是否经皮......
