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Development of a pyrF-based counterselectable system for targeted gene deletion in Streptomyces rimo
Streptomyces produces many valuable and important biomolecules with clinical and pharmaceutical applications. The develo......
从链霉菌YN17707菌株发酵物中,通过活性跟踪分得三个elaiophylin类新细胞周期抑制剂及细胞凋亡诱导剂elaiophylin、11-O-monomethyl......
结核病耐药问题十分严重,传统的药敏实验需1~2月。Sm是一线抗结核的药物,结核分支杆菌对Sm最常见的分子机制是由于核糖体S12蛋白编码基因(spsL)突变。......