目的 验证6-氧-甲基鸟嘌呤-DNA甲基转移酶(MGMT)基因启动子CpG岛高甲基化在结直肠癌发生、发展中的作用,并探讨联合检测基因甲基化......

The tumor selectivity of alkylating agents that produce guanine O6-chloroethyl (laromustine and carmustine) and O6-methy......

O6-methylguanine-DNA methyltransferase (MGMT) plays an important role in repairing alkylated DNA. MGMT activity as well ......